Research Interests

My main research involves advanced diffusion NMR/MRI methods for probing microstructural features of tissues, such as cell size, shape, organization, cell-membrane permeability and microcirculation. I’m particularly interested in non-invasive multidimensional diffusion encoding approaches, which allow teasing apart different tissue features and thus provide highly specific information useful in research and in clinical applications. Within the C-MORPH project at DRCMR, I’m focusing mainly on time-dependent diffusion effects in tensor-valued encoding and exploring possibilities of using these effects to access novel microstructural information

Contact Details

Samo Lasic

Research Fellow

+46 7 6142 1992

samol@drcmr.dk

Research Areas

Advancing Biomedical MRI

Research Groups

Microstructure & Plasticity

Neurofluids

See Full CV here

Employments

2019 – Present	Senior Researcher, DRCMR
2018 – Present	Head of Technology Development at Random Walk Imaging
2016 – 2018	Chief scientific officer at Random Walk Imaging
2014 – 2016	Vinnova (Marie-Curie) fellow - visiting reasercher at the The Danish Research Centre for Magnetic Resonance (DRCMR)
2009 – 2016	Key Account Manager and Project Manager for OncoPulse at CR Development, NMR expert at CR Competence, AB
2007 – 2009	Postdoc at Physical Chemistry, Lund University, Sweden
2002 – 2007	Collaboration with science center Hiša Eksperimentov
2001 – 2007	Assistant professor for physics at Faculty for Mathematics and Physics, University of Ljubljana, Slovenia
2001 – 2007	Leading workshops within the program for high school in-service teachers training at Faculty for Mathematics and Physics, University of Ljubljana, Slovenia
2000 – 2001	Teaching physics at the Bežigrad high school, Ljubljana, Slovenia

Education

2006	PhD in Physics, Faculty of Mathematics and Physics, University of Ljubljana, Slovenia
2001	MSc in Physics, Faculty of Mathematics and Physics, University of Ljubljana, Slovenia

Publications

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Lasič S, Just N, Nilsson M, Szczepankiewicz F, Budde M & Lundell H, Spectral principal axis system (SPAS) and tuning of tensor-valued encoding for microscopic anisotropy and time-dependent diffusion in the rat brain

map[#text:Imaging Neuroscience -lang:en]

Imaging Neuroscience vol 3, IMAG.a.35, (2025). DOI:10.1162/IMAG.a.35

Lasič S, Chakwizira A, Lundell H, Westin C & Nilsson M, Tuned exchange imaging: Can the filter exchange imaging pulse sequence be adapted for applications with thin slices and restricted diffusion?,

[map[#text:NMR in Biomedicine -lang:en] map[#text:N M R in Biomedicine -lang:en] map[#text:N M R in Biomedicine (Online) -lang:en]]

vol 37, Issue 11, p. 1-22, (2024). DOI:10.1002/nbm.5208

Ohene Y, Harris WJ, Powell E, Wycech NW, Smethers KF, Lasič S, South K, Coutts G, Sharp A, Lawrence CB, Boutin H, Parker GJM, Parkes LM & Dickie BR, Filter exchange imaging with crusher gradient modelling detects increased blood-brain barrier water permeability in response to mild lung infection

[map[#text:Fluids and Barriers of the CNS -lang:en] map[#text:Fluids and Barriers of the C N S -lang:en] map[#text:Cerebrospinal Fluid Research -lang:en]]

vol 20, Issue 1, p. 1-18, (2023). DOI:10.1186/s12987-023-00422-7

Chakwizira A, Westin C, Brabec J, Lasič S, Knutsson L, Szczepankiewicz F & Nilsson M, Diffusion MRI with pulsed and free gradient waveforms: Effects of restricted diffusion and exchange,

[map[#text:NMR in Biomedicine -lang:en] map[#text:N M R in Biomedicine -lang:en] map[#text:N M R in Biomedicine (Online) -lang:en]]

vol 36, Issue 1, p. 1-22, (2022). DOI:10.1002/nbm.4827

Lasič S, Yuldasheva N, Szczepankiewicz F, Nilsson M, Budde M, Dall’Armellina E, Schneider JE, Teh I & Lundell H, Stay on the Beat With Tensor-Valued Encoding: Time-Dependent Diffusion and Cell Size Estimation in ex vivo Heart,

map[#text:Frontiers in Physics -lang:en]

Frontiers in Physics vol 10, p. 1-19, (2022). DOI:10.3389/fphy.2022.812115

Andersen KW, Lasič S, Lundell H, Nilsson M, Topgaard D, Sellebjerg F, Szczepankiewicz F, Siebner HR, Blinkenberg M & Dyrby TB, Disentangling white-matter damage from physiological fibre orientation dispersion in multiple sclerosis

map[#text:Brain communications -lang:en]

Brain communications vol 2, Issue 2, p. 1-14, (2020). DOI:10.1093/braincomms/fcaa077

Lundell H, Nilsson M, Dyrby TB, Parker GJM, Cristinacce PLH, Zhou F, Topgaard D & Lasič S, Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail

[map[#text:Scientific Reports -lang:en] map[#text:Scientific Reports -lang:en]]

vol 9, Issue 1, p. 1-12, (2019). DOI:10.1038/s41598-019-45235-7

Lasič S, Lundell H, Topgaard D & Dyrby TB, Effects of imaging gradients in sequences with varying longitudinal storage time-Case of diffusion exchange imaging

[map[#text:Magnetic Resonance in Medicine -lang:en] map[#text:Journal of Magnetic Resonans in Medicine -lang:en] map[#text:Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine -lang:en] map[#text:Magnetic Resonance medicine -lang:en]]

vol 79, p. 2228-2235, (2018). DOI:10.1002/mrm.26856

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